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KMID : 0870420090130020109
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2009 Volume.13 No. 2 p.109 ~ p.113
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Renal Carcinoma Cell Metastasis into Pancreas
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Cha Jang-Ho
Kim Jae-Keun
Lee Woo-Jung
Chi Hoon-Sang
Park Joon-Seong
Yoon Dong-Sup
Hwang Ho-Kyung
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Abstract
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Introduction: Renal cell carcinoma (RCC) is a relative rare tumor, accounting for approximately 3% of adult malignancies. Renal cell carcinoma has a high metastatic potential and is renowned for its ability to spread to almost any organ of the body. Pancreas is a rare site for metastasis from other primary cancers. Moreover, pancreatic metastasis is difficult to differentiate and may be misdiagnosed as a primary pancreatic cancer. The aim of this study was to review our cases of renal cell carcinoma that had metastasized to the pancreas after radical nephrectomy.
Methods:We did a retrospective review of the records of 4 patients with pathologically confirmed RCC that had metastasized to the pancreas after radical nephrectomy.
Results:Our group of 4 patients consisted of 2 men and 2 women. Their average age was 58.7 years (± 10.51 years). The locations within the pancreas were the head, in 2 (50.0%) andthe body/tail in 2 (50.0%) patients. The pancreatic metastases were treated by pancreaticoduodenectomy in 2 patients, and by distal pancreatectomy in 2 patients. Median
survival duration was 109.0 (± 67.3 months) "Median" is associated with an interquartile range (25% to 75%). The number 67.3 appears to be a standard deviation which is associated with the "mean".
Conclusions: RCC is an unpredictable tumor that may result in a late metastasis even from an early stage. Aggressive surgical management of pancreatic lesions offers a chance of long-term survival.
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KEYWORD
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Renal cell carcinoma, Pancreas, Metastasis, Pancreatectomy
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